Importin α

Contains 2 domains:

  • IBB Domain:  basic N-terminal importinß-binding domain
  • Arm domain that contains an NLS 

(Macara 2001)

 

Importin α binds classical NLSs of cargo proteins.  It also binds importin ß, which interacts with components of the nuclear pore to mediate the transport of the complex to the nucleus (Macara 2001).

Back to Importins page

Home   Introduction   Questions about Nuclear Transport   Nuclear Pore Complex   Protein Export   Protein Import   Nuclear Localization Signal   Nuclear Export Signal   Ran   Proposed Project   References