Course Description |
Course Schedule The Course Schedule Items listed in italics are 10-15 min. lectures. This course was scheduled over the week that included the July 4th holiday, Therefore, the schedule that appears here is for a four-day week. All homework is described in the section on "Out of Class Assignments." |
The Friday before
Introductions Pre-test Homework: Reading assignment, military system design Monday Morning Discuss military defense system Introduction to Immunology Introduction to case scenarios and first data sets Group assignments Group discussions Research time Monday Afternoon Introduction to laboratory safety Bacterial Isolation and plating exercise Provide patient fluid samples for culturing Gram staining and microscopy* Microbial pathogenesis and immune defenses Epidemiology outbreak simulation Homework: Solve epidemiology exercise, online reading assignments Tuesday Morning Homework answers and discussion Humoral immunology and antibodies Presentation of new case details and samples Ouchterlony setup Streak for antibiotic susceptibility testing (if appropriate) Viral plaque assay (if appropriate) Analyze plates from previous day Selection of organisms to test against patient serum by Western blot Tuesday afternoon Presentaion of new samples and epidemiology data Western blots the following is done while Westerns are incubating T-cells and cell-mediated immunology group discussion/data analysis of case scenarios Homwework: vaccination and ethics of research web sites Wednesday morning Results from previous day Group analysis and review of previous day's results and data Design and request other tests on patient samples** Begin group analysis of data Design ELISA experiment (samples, controls, what will be on the plate, etc.) Wednesday afternoon ELISA Immune regulation, auto immunity, allergy Ethics of research and vaccination discussion Draw audience assignments, explanation of grading Thursday morning Presentations Thursday afternoon Defense system design/immunology application wrap=up Post-test Science Game Show |
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* Gram staining was available to students throughout the week
and several groups took advantage of this to examine specimens that grew
later. One group also performed an india ink stain to look for a fungal
capsule.
** Students were allowed to submit detailed requests for other experiments to be performed on patient or site samples. Appropriate results were generated by the instructors after the lunch break on the day requested. This allowed for students to analyze data that we lacked either the time or resources to have them generate. |
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