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Multifunctional nanocarrier for cancer therapy

 

 

Luminescent carbon nanotubes by surface functionalization

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Laboratories of Energy Materials and Nano Biomedicine

Design of Intelligent Nanosystems to Address Critical Issues in Medical and Life Sciences
Search for New Mechanisms, Structures, and Properties in Advanced Energy Materials


DShi

Laboratories of Energy Materials and Nano Biomedicine design and develop novel structures and materials for discovery of new properties in fundamental studies and engineering of key applications in energy and biomedicine.

The current NSF research projects can be seen from the links below


Dr. Donglu Shi was awarded the George Rieveschl Jr. Award for Distinguished Scientific Research from UC in 2023.

For Dr. Shi's National Science Foundation supported research programs, please visit:
https://ceas.uc.edu/research/centers-labs/energy-materials-and-nano-biomedicine/recent-research.html

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DShi

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DShi

Research_supported_by_NSF_1953009

Optical thermal insulation via the photothermal effects of Fe3O4 and Fe3O4@Cu2-xS thin films for energy-efficient single-pane windows MRS Communications, 2020

DShi
Research_supported_by_NSF_1635089


DShi

Research_supported_by_NSF_1953009

Dr.Shi's current NSF research on plasma virus disinfection can be viewed at:
https://ceas.uc.edu/research/centers-labs/energy-materials-and-nano-biomedicine/recent-research.html

DShi Research_supported_by_NSF_2029268


DShi


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DShi

Circulating tumor cell isolation for cancer diagnosis and prognosis, eBioMedicine, 2022

Nanoparticle Delivery Systems with Cell-Specific Targeting for Pulmonary Diseases, American Journal of Respiratory Cell and Molecular Biology, 2021

Dual targeting with cell surface electrical charge and folic acid via superparamagnetic Fe3O4@Cu2-xS for photothermal cancer cell killing , Cancers, 2021

Highly Efficient In Vivo Targeting of the Pulmonary Endothelium Using Novel Modifications of Polyethylenimine: An Importance of Charge, Advanced Healthcare Materials, 2018


Media reports on the novel Janus nanostructures that we have recently developed for targeted drug delivery:

 Dual Surface-Functionalized Janus Nanocomposities of Polystyrene/Fe3O4@SiO2 for Simultaneous Tumor Cell Targeting and Stimulus-Induced Drug Release

The American Ceramic Society

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Representative Publications

 

 Photothermal Utility Heating with Diffused Indoor Light via Multiple Transparent Fe3O4@Cu2-xS Thin Films

(Energy Technology 2024)

 A photothermal solar tunnel via multiple transparent Fe3O4@Cu2-xS thin films for heating utility application

(Solar Technology 2024)

 Fluorinated amphiphilic Poly(??-Amino Ester) Nanoparticle for Highly Efficient and Specific Delivery of Nucleic Acids to the Lung Capillary Endothelium

(Bioactive materials 2024)

 Biomedical Applications of Cold Atmospheric Plasma: Cancer Therapy and Virus Inactivation

(Nano LIFE 2024)

 Solar harvesting through multiple semi-transparent cadmium telluride solar panels for collective energy generation

(Solar Energy 2023)

 Inactivation of SARS-CoV-2 on Surfaces by Cold-Plasma-Generated Reactive Species

(Bioengineering 2023)

 Lung endothelial cells regulate pulmonary fibrosis through FOXF1/R-Ras signaling

(Nature Communications 2023)

 Demonstration of Safety in Wild Type Mice of npFOXF1, a Novel Nanoparticle-Based Gene Therapy for Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins

(Biologics: Targets and Therapy 2023)

 Enhanced Silicon Photovoltaic Efficiency by Solar Light Spectral Modulation via Photonically Tuned Porphyrin-Iron Oxide Hybrid Thin Films

(Energy Technology 2023)

 3D Solar Harvesting and Energy Generation via Multilayers of Transparent Porphyrin and Iron Oxide Thin Films

(Energies 2023)

 Inactivation of SARS-CoV-2 on Surfaces by Cold-Plasma-Generated Reactive Species

(Bioengineering 2023)

 Improving anti-tumor efficacy of low-dose Vincristine in rhabdomyosarcoma via the combination therapy with FOXM1 inhibitor RCM1

(Frontiers in Oncology 2023)

 Effect of Dipole Interactions on Blocking Temperature and Relaxation Dynamics of Superparamagnetic Iron-Oxide (Fe3O4) Nanoparticle Systems

(Materials 2023)

 Solar harvesting and energy generating building skins with photothermal-photovoltaic modality based on porphyrin thin films

( MRS Communications 2022)

 Circulating tumor cell isolation for cancer diagnosis and prognosis

(eBioMedicine 2022)

 Transparent porphyrin-based hybrid films for spectral selective solar harvesting and energy generation

(Solar Energy Materials and Solar Cells 2022)

 Entrapment of Airborne Particles via Simulated Highway Noise-Induced Piezoelectricity in PMMA and EPDM

(Energies 2022)

 Solar Desalination via Multilayers of Transparent Photothermal Fe3O4@Cu2-xS Thin Films

(Energy Technology 2021)

 Dual targeting with cell surface electrical charge and folic acid via superparamagnetic Fe3O4@Cu2-xS for photothermal cancer cell killing

(Cancers 2021)

 Photothermal and photovoltaic properties of transparent thin films of porphyrin compounds for energy applications

(Applied Physics Reviews 2021)

 Solar harvesting through multilayer spectral selective iron oxide and porphyrin transparent thin films for photothermal energy generation

(Advanced Sustainable Systems 2021)

 Nanoparticle Delivery Systems with Cell-Specific Targeting for Pulmonary Diseases

(American journal of respiratory cell and molecular biology 2021)

 How effective is a mask in preventing COVID-19 infection?

(Medical devices & sensors 2021)

 Photonically-Activated Molecular Excitations for Thermal Energy Conversion in Porphyrinic Compounds

(The Journal of Physical Chemistry C 2020)

 Optical thermal insulation via the photothermal effects of Fe3O4 and Fe3O4@Cu2-xS thin films for energy-efficient single-pane windows

(MRS Communications 2020)

 Processing of soft magnetic fine powders directly from as-spun partial crystalline Fe77Ni5.5Co5.5Zr7B4Cu ribbon via ball mill without devitrification.

(IEEE Transactions on Magnetics 2020)

 Light angle dependence of photothermal properties in oxide and porphyrin thin ?lms for energy-ef?cient window applications.

(MRS Communications 2020)

 Nanoparticle Delivery of Proangiogenic Transcription Factors into the Neonatal Circulation Inhibits Alveolar Simplification Caused by Hyperoxia.

(American journal of respiratory and critical care medicine. 2020)

 The S52F FOXF1 Mutation Inhibits STAT3 Signaling and Causes Alveolar Capillary Dysplasia.

(American journal of respiratory and critical care medicine. 2019)

 Effective reduction of building heat loss without insulation materials via the photothermal effect of a chlorophyll thin film coated "Green Window"

(MRS Communications 2019)

 Highly Efficient In Vivo Targeting of the Pulmonary Endothelium Using Novel Modifications of Polyethylenimine: An Importance of Charge

(Advanced Healthcare Materials 2018)

 "Minimalist" Nanovaccine Constituted from Near Whole Antigen for Cancer Immunotherapy

(ACS Nano 2018)

 Nanomaterials for Cancer Precision Medicine

(Advanced Materials 2018)

 Fever-Inspired Immunotherapy Based on Photothermal CpG Nanotherapeutics: The Critical Role of Mild Heat in Regulating Tumor Microenvironment

(Advanced Science 2018)

 Photothermal effect on Fe3O4 nanoparticles irradiated by white-light for energy efficient window application

(Solar Eng. Mat. & Solar Cells 2017)

 Biomarkerless targeting and photothermal cancer cell killing by surface-electrically-charged superparamagnetic Fe3O4 composite nanoparticles

(Nanoscale 2017)

 Targeting and Regulating of an Oncogene via Nanovector Delivery of MicroRNA using Patient-Derived Tumor Xenografts

(Theranostics 2017)

 Targeting Negative Surface Charges of Cancer Cells by Multifunctional Nanoprobes

(Theranostics 2016)

 A Graphene Quantum Dot (GQD) Nanosystem with Redox-Triggered Cleavable PEG Shell Facilitating Selective Activation of Photosensitiser for Photodynamic Therapy

(RSC Advances 2016)

 A Multimodal System with Synergistic Effects of Magneto-Mechanical, Photothermal, Photodynamic and Chemo Therapies of Cancer in Graphene-Quantum Dot-Coated Hollow Magnetic Nanospheres

(Theranostics 2016)

 Photo-fluorescent and Magnetic Properties of Iron Oxide Nanoparticles for Biomedical Applications

(Nanoscale 2015)

 Disulfide-Bridged Cleavable PEGylation in Polymeric Nanomedicine for Controlled Therapeutic Delivery

(Nanomedicine 2015)

 Photoluminescence and Photothermal Effect of Fe3O4 Nanoparticles for Medical Imaging and Therapy

(App. Phys. Lett. 2014)

 Dual Surface-Functionalized Janus Nanocomposities of Polystyrene/Fe3O4@SiO2 for Simultaneous Tumor Cell Targeting and Stimulus-Induced Drug Release

(Adv. Materials 2013)

 A Versatile Multicomponent Assembly via β-cyclodextrin Host-Guest Chemistry on Graphine for Biomedical Applications

(Small 2012)

 Engineered Redox-Responsive PEG Detachment Mechanism in PEGylated Nano-Graphine Oxide for Intracellular Drug Delivery

(Small 2012)

 Engineered Multifunctional Nanocarriers for Cancer Diagnosis and Therapeutics

(Small 2011)

 Fluorescent, Superparamagnetic Nanospheres for Drug Storage, Targeting, and Imaging: A Multifunctional Nanocarrier System for Cancer Diagnosis and Treatment

(ACS Nano. 2010)

 Integrated Multifunctional Nanosystems for Medical Diagnosis and Treatment

(Adv. Funct. Materials 2009)

 Fluorescent Polystyrene-Fe3O4 Composite Nanospheres for In Vivo Imaging and Hyperthermia

(Adv. Materials 2009)

 5f-6d orbital hybridization of trivalent uranium in crystals of hexagonal symmetry: Effects on electronic energy levels and transition intensities

(Phys. Rev. B 2009)

 In vivo Imaging and Drug Storage by Quantum-Dot-Conjugated Carbon Nanotubes

(Adv. Funct. Materials 2008)

 Nanoscale Solute Partitioning in Bulk Metallic Glasses

(Adv. Materials 2008)

 Effects of plasma surface modification on interfacial behaviors and mechanial properties of carbon nanotube-Al2O3 nanocomposites

(Appl. Phys. Lett. 2007)

 Neutron diffraction study of the structure and low-temperature phase transformation in ternaty NiAl + M (M=Ni, Fe, Co) allows

(Scripta Materialia 2007)

 In Vivo Imaging by Luminescent Nanotubes

(Adv. Materials 2007)

 Luminescent Carbon Nanotubes by Surface Functionalization

(Adv. Materials 2006)

 Processing Dependence of Texture, and Critical Properties of YBa2Cu3O7-δ Films on RABiTs Substrates by a Non-Fluorine MOD Method

(J. Am. Ceram. Soc. 2006)

 Strontium-Induced Oxygen Defect Structure and Hole Doping in La2-xSrxCuO4

(Phys. Rev. Lett. 1991)

 Synthesis, structure and superconductivity in the Ba1-xKxBiO3-y system

(Nature 1988)

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